KEY FEATURES: THE NEXT GENERATION OF FOCUS NOOTROPICS
TOTAL FOCUS is the result of a five year long global research quest for the next-generation mental & physical energy ingredients.Total Focus is the first ever focus nootropic and smart drug that includes Zynamite - a patent pending ingredient sourced from mango leaves that activates brain activity similar to caffeine, but acts non-selectively to modulate feelings of smooth, intense focus, concentration, and memory without any of the side effects associated with heavy caffeine use. Imagine no longer having to choose between feeling focused and having to risk your health while doing so. This is the power of Total Focus.
FAST ACTING & LONG LASTING FOR IMMEDIATE AND PROLONGED LASER FOCUS Designed to start working within 15 minutes and with a 4x longer half life than any other traditional nootropics and stimulants to support you at the start, during, and for the full entirety of your work. Users have reported achieving intense levels of flow state, deep concentration, and positive mood at times they usually would quit, that lasts well beyond 10 hours.
INCREASE REACTION TIME & ENHANCED PROCESSING SPEED DURING TIMES OF FATIGUE All the research done on TOTAL FOCUS was built around adapting during times of extreme stress and fatigue. TOTAL FOCUS is the unique solution for working professionals, entrepreneurs, athletes, e-sport gamers, shift workers, truck drivers and every person in need of mental and physical energy during times of extreme fatigue.
NO BS HYPE. SUPPORTED BY 3 GLOBAL INDUSTRY AWARDS + 7 CLINICAL STUDIES + 5 PEER REVIEWED PAPERS & 3 PENDING PATENTS Over 90%+ of supplements sold are based on anecdotal evidence and no reputable studies. Zynamite® is the result of a five year long global research quest for the next-generation mental & physical energy ingredient. The ingredients in TOTAL FOCUS have won the NUTRA INGREDIENTS AWARD in both 2018, and 2019 and awarded the Frost & Sullivan New Product Innovation Award in 2019. The ingredients in TOTAL FOCUS hold over 4 Patents, and have been tested in over 7 clinical studies and included as scientific evidence in over 5 peer reviewed publications.
GRAS & SIDE-EFFECT FREE TESTED BY THIRD PARTY LAB FOR PURITY MADE IN TEXAS, USA Every batch of TOTAL FOCUS is manufactured, sealed, and packaged at our cGMP & FDA REGISTERED partner facility in Texas, USA. Each batch is only released after passing purity testing passing all microbial, heavy metal, and spec.
WHAT ARE THE INGREDIENTS IN TOTAL FOCUS?
Zynamite®: 200 mg
Zynamite® is Nektium’s patent-pending proprietary Mangifera indica extract standardized to ≥ 60% mangiferin. Mangifera indica, the common mango tree, is cultivated extensively in the tropical and subtropical regions of the world. Infusions and decoctions of mango leaves are used extensively in traditional health systems and have been known for centuries for their health benefits.
Zynamite® activates brain waves and increases Long Term Potentiation in a remarkably similar pattern to caffeine. While caffeine antagonizes adenosine receptors, Zynamite® acts non-selectively to stimulate brain activity. The key active, mangiferin acts non-selectively to modulate multiple physiological and CNS targets.Intriguingly, in vivo studies of Zynamite® have pointed to the potential for synergies between Zynamite® and low doses of caffeine, suggesting that formulations that combine these ingredients will be attractive to consumers.
PurCaf® Organic Caffeine: 50 mg Nearly all caffeine found in traditional supplements is manufactured with syntethic, lab-made caffeine. In Total FOCUS, we have used PurCaf instead. PurCaf® is the ONLY trademarked organic caffeine formula and is 100% organic, gluten free, chemical free, and vegetarian-friendly. PurCaf® is non-GMO and one of the only GRAS caffeine sources in the industry today for safe use. Each serving of TOTAL FOCUS contains 50 mg of pure organic caffeine that is water extracted from green (unroasted) coffee beans to give you a pure, clean rush of caffeine to help ramp up your energy levels and supercharge your levels of focus.
Rhodiola Rosea (3% Rosavins) 200 mg Rhodiola rosea is a herb in the rhodiola genera (Crassulaceae family) which has traditional usage as an anti-fatigue agent. Rhodiola appears to be able to significantly reduce the effects of prolonged and minor physical exhaustion that results in fatigue. This is more related to stress and the 'burnout' effect, or prolonged but low intensity physical exercise. The Rhodiola used in TOTAL FOCUS was produced by Nektium, one of the world's leading ingredient manufacturers of high-quality Rhodiola Rosea extracts. Nektium is one of a few select companies that are authorized by a special permit issued by the Russian Government to export Rhodiola Rosea from the pristine Altai Mountains in Siberia.
IS TOTAL FOCUS SAFE?
Every batch of TOTAL FOCUS is manufactured, sealed, and packaged at our cGMP & FDA REGISTERED partner facility in Texas, USA. Each batch is only released after passing purity testing passing all microbial, heavy metal, and spec.
When it comes to capsules, companies have two main choices: a gelatin or a veggie capsule. Gelatin capsules are made of gelatin, which is an animal by-product formed from collagen, often from the hooves, bones, and connective tissue of pigs and cows. AZOTH® uses vegetable capsules, which are derived from a plant by-product called cellulose. Vegetable capsules can be used by those following a strict vegetarian or vegan lifestyle.
WHAT IS THE STORY BEHIND TOTAL FOCUS?
The last time we came out with a product was in 2017, three years ago. So, when we make a product, we mean business. We have a simple mission: Help people get more sh*t done. AZOTH 2.0 was the staple to accomplishing that, but for those who want to take their focus to the next level, TOTAL FOCUS will be an untouchable add-on.
When looking for focus supplements, consumers have had to choose either for shots and drinks which are filled with harmful ingredients, cause jitters, headaches, and other side-effects or for healthier alternatives which are so watered down, that they don’t do anything. TOTAL FOCUS is the result of a five year long global research quest for the next-generation mental & physical energy ingredient that delivers on effectiveness and health.
In America alone, 400 million cups of coffee are consumed per day. It should not come to any surprise that the $122B supplement industry has been using caffeine heavily in their products and has been working overtime to find a powerful replacement for the drug.
Four years ago, after noting the worrying global trend of increasing adverse reactions from excessive consumption of highly caffeinated products, Nektium's R&D and innovation team began a global search for a safe and effective ingredient that could not only replace caffeine, but be superior to caffeine.
The challenge? A research imperative to find rapidly acting botanical extract with nootropic and sports performance activities, free of cardiovascular and other side-effects, and without addictive and tolerance potential.
Nektium's research team was led by Dr. Nigel Gericke, and involved extensive reviews of the international ethnobotanical literature, of the uses of plants in the traditions of Ayurvedic Medicine and Traditional Chinese Medicine, and reviews of Nektium's own ethnobotanical records from European, Russian, Amazonian, and African plants.
The result: Zynamite, a specialized extract from Mango Leaves which notably showed precisely but remarkably similar activation activity to caffeine in studies of brain electrical activity, with one caveat: it acts selectively.
While caffeine antagonizes adenosine receptors, Zynamite acts non-selectively to stimulate brain activity. The key active, mangiferin acts non-selectively to modulate multiple physiological and CNS targets.
What does this mean? Simple: while Zynamite can increase levelf of mental energy, cognition, and concentration, it may do so without increasing levels of cortisol - which then equates to fewer (if any) side effects usually caused by caffeine.
This hypothesis was rigorously tested.
The Studies: Zynamite Delivers Zynamite has been studied in 4 randomized, placebo-controlled clinical trials - 2 for mental energy and 2 for sports performance.
In the first study, twelve physically active young men took a combination of 140mg Zynamite® + 50mg luteolin every 8 hours, and after 48 hours, they performed repeated bicycle ergometer Wingate sprint tests. Mean power output was increased by 5–7% compared with placebo (Figure 1).
In a follow-up confirmatory study, 30 young athletes (13 women and 17 men), 140mg of Zynamite was administered every 8 hours for 48 hours, but this time in two separate combinations: 50mg luteolin and 600mg quercetin.
The combination of Zynamite pre workout capsules with quercetin increased peak power output by 19.4% compared to placebo. Both formulations increased mean power output by 6% during repeated ergometer Wingate tests. Zynamite® improved VO2 peak by 5%, with a corresponding increase in brain oxygenation of 10–12% in women.⁷ (Figure 2)
The results from these two studies demonstrated that formulations containing Zynamite have an even stronger effect than those published for caffeine, in addition to a significant improvement in peak power output.
Zynamite's Effects on Mental Energy The next two studies focused on mental energy. The first used a single dose of 500mg of in 16 participants (7 men and 9 women).
The study showed that Zynamite significantly reduced fatigue after only 1.5 hours, analyzed with the Profile of Mood States questionnaire (POMS). Zynamite reduced stress during the Calculation Performance Tests, evidenced by Galvanic skin response. (Figure 3) Zynamite had no side effects and no change in heart rate variability or blood pressure over the course of the study-variables typically affected by caffeinated products.
During performance of two cognitively demanding challenges, a Number Sequence Test (NST) and a Number Connection Test (NCT), Zynamite® had a significant activating effect on the brain compared to placebo as determined by frequency analysis of the changes in electrical activity across six brain wave frequency ranges (colour coded) in the EEG of the association cortex (change from time-averaged baseline assigned as 100%) ; significance values: ** p<0.05, *** p<0.001. (Figure 4)
In a nutshell, what the team at Nektium was able to accomplish - was to finally decrease the dillemma of sacrificing health and levels of well-being for temporary increases in focus and energy. This is truly groundbreaking.